This recruitment is now CLOSED

PhD Studentships in Genomic and Environmental Medicine

We are pleased to invite applications for three year PhD studentships based within Genomic and Environmental Medicine at the National Heart and Lung Institute (NHLI), Imperial College. These are jointly funded by the Medical Research Council Centre for Environment and Health (MRC-CEH) and NHLI.

The MRC-CEH trains and develops the next generation of academic and policy leaders in the field of environment and health research. These PhDs in addition will focus on development of knowledge /skills within the field of respiratory health. Successful candidates will be supported by a training programme within the MRC-CEH and within Imperial College.

The NHLI-based group utilises large scale population/occupational-based epidemiological studies and ‘big data’ (e.g. primary care electronic health records). Research includes:

  • occupational causes of respiratory disease, work-related respiratory disability; laboratory-based investigations of occupational allergy/immunology;
  • national and international (including low and middle income countries) cross-sectional/cohort studies of asthma, allergy and COPD
  • role of indoor/outdoor pollutants and vegetation (pollen, green spaces) on respiratory disease
  • investigation of genetic risk factors for respiratory disease

RESEARCH AREAS

We are looking for outstanding candidates with an interest in environmental research as related to respiratory health with experience in, at least one of, the following research areas:

  • Observational epidemiology
  • Medical/bio statistics, statistical genetics
  • Epidemiology of occupational lung disease
  • Non-communicable respiratory disease and global health
  • Molecular signatures of exposures and disease pathways
The effect of the indoor environment on asthma and chronic obstructive pulmonary disease (COPD).
This project will use data from the European Community Respiratory Health Survey (ECRHS) to test the hypothesis that adverse indoor exposures have a detrimental effect on the onset and exacerbation of asthma and COPD. Primary Supervisor: Dr Andre Amaral; Co-supervisor: Dr Elaine Fuertes

The role of pollen and pollution on asthma severity and progression using large population-based epidemiological studies in the UK.
This project will use routinely collected de-identified primary care electronic healthcare record data as well as data from the large UK Biobank cohort to explore the relationship between pollen and pollution, as well as their interaction, on the incidence and progression of asthma. Primary Supervisor: Prof. Jennifer Quint; Co-supervisor: Dr Elaine Fuertes

ELIGIBILITY

Candidates should hold, or achieve by the start of the programme, a Master's degree in addition to a Bachelor's degree with a UK First- or Upper Second-Class honours grade or equivalent in a relevant life science or quantitative science subject. Candidates must have strong statistical/computational skills.

Candidates MUST start the PhD by 1st April 2023 at the latest.

Applications from unsuccessful candidates in previous recruitment rounds for MRC-CEH studentships will not be considered.

Studentships include funding for Home tuition fees and a stipend of £19,668 per annum.

  • All UK/EU/International candidates are eligible to apply for these studentships. 
  • International candidates (i.e. all non-UK nationals) that are successfully awarded one of these studentships MUST cover the difference between Home and International tuition fees.  Please see here information on current PhD tuition fees.

APPLICATION

The application form can be Downloaded Here. It should be completed electronically and e-mailed to a.amaral@imperial.ac.uk. (Queries can be emailed to Professor Deborah Jarvis (d.jarvis@imperial.ac.uk).

Applicants with relevant knowledge, skills and ambition outside the scope of the projects listed are encouraged to apply (relevant projects will be identified following successful interview).

Incomplete applications will not be considered.

The closing date for applications is 30 November 2022. 

Applicants unable to attend interview in person will undergo an online interview and be invited for a second face-to-face meeting before confirmation of offer.

The MRC Centre and the NHLI are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment.