Below is a list of Studentship Opportunities including the associated supervisors, project titles and further information.

 

Mechanistic Research in Environment and Health

Ageing is one of the principal risk factors for non-communicable disease and the decline in physiologic function. It has been proposed that DNA methylation may represent a good predictor of age-related diseases and mortality risk and therefore in this study we wish to examine whether long-term exposure to urban air pollution, particularly that derived from traffic emissions, promote these age-related changes. This project will be supervised by  Dr Ian Mudway (Imperial College London) and  Dr Oliver Robinson and will align with the  Children’s Health in London and Luton and  Airwave cohorts . A strong background in molecular sciences and bioinformatics would be desirable prerequisites for this project, which aligns with the Molecular Signatures and Disease Pathways theme within the MRC Centre for Environment & Health and the Air Pollution and Health and the Biomarkers of exposure and effect themes within the Health Protection Research Unit in Environmental Exposures & Health.

Epidemiology and Exposure Assessment

To respond to the growing housing needs brownfield sites are increasingly being targeted for housing redevelopment. Depending on their previous use, ex-brownfield sites might pose potential risks to the health of residents in housing developments either in, on or in the vicinity of, redeveloped sites. This PhD will identify ex-brownfield sites in the UK, with a focus on redeveloped ex-gasworks sites, develop an exposure assessment of affected populations and conduct epidemiological analysis on potential adverse health effects. This project is supervised by Dr Daniela Fecht (Imperial College London). It is aligned with the In vitro testing and integration with epidemiological data theme within the Health Protection Research Unit in Chemical and Radiation Threats and Hazards.

Epidemiology and Exposure Assessment at NHLI

This project will examine the role of indoor and outdoor bioaerosol exposures on the onset and exacerbation of asthma and COPD, as well as other adult respiratory and allergic health outcomes. This may include examining high-risk subgroups, genetic susceptibility, and the effect of combined exposures or interactions between indoor and outdoor factors. It will use data from cohorts and data sources available within the MRC Centre with opportunities for new data collection.
This project will examine the role of workplace exposures in chronic lung diseases in available cohorts including the Burden of Obstructive Lung Disease (BOLD) study. BOLD has information from adults in several low- and middle-income countries (LMICs) and in UK Biobank. The student may also develop a new tool suitable for collection of lifetime job histories in LMICs .
This project will examine the relationship between respiratory health and environmental factors (e.g., household air pollution from biomass use; outdoor air pollution; vegetation index; pesticide use) in LMICs using baseline and follow-up data from the Burden of Obstructive Lung Disease (BOLD) study. BOLD collected high-quality post-bronchodilator lung function data and information on risk factors from about 30,000 people from 41 sites, mostly in LMICs. There will be opportunities for new data collection.